Vitamin Retailer November 2011 : Page 56

2011 Science of Supplements NaturaNectar LLC 1560 Sawgrass Corporate Pkwy., 4th Floor • Sunrise, FL 33323 • Phone: (800) 609-7794 Websites:;; Aglycone Isoflavones: A More Efficient Natural Menopause Management First the Facts: • More than 43 million women in the U.S. alone are going through menopause. • 75 percent of menopausal women experience hot flashes and or night sweats. • About a third of those have severe symptoms. • The findings from the Women’s Health Initiative over the last 10 years confirmed the risks of hormone replace-ment therapy (HRT). high quality not-geneti-cally engi-neered fer-mented soy. Such unique combination of aglycone3 isoflavones are not pres-ent in any other prod-uct available today. pounds that resemble the chemical structure of the hormone estrogen but still are not hormones. They bind well to the women’s hormone cell receptors and provide relief from their menopausal symptoms.* The Change When it comes to what women call “the change,” they know that being raised and living in the Western world, espe-cially in America is a great disadvan-tage. We are talking about the life changing period called menopause or the years before and after the date which marks 365 days past since a woman had her last period. These years are know as peri-menopause and post-menopause and are marked by a grad-ual decline in the women’s ability to pro-duce sex hormones, especially estrogen. This gradual decline causes hormone cell receptors to send “hormone starva-tion” signals to the brain creating symp-toms like hot flashes, night sweats, irri-tability and dryness of skin, to name a few. Asian women have been observed to be able to go through menopause with far less discomforts than western women. 5,6 Research shows correlation between their diet—which is rich in legumes, especially soy—and the small-er incidence of menopausal symptoms. 5,6 NaturaNectar’s decade long research work on Brazilian Red Bee Propolis through its partnership with University of São Paulo scientists, has identified this exotic type of bee propolis of being rich in aglycone isoflavones, 3 natural com-pounds used in EaseFemin. Glucosides x Aglycone Isoflavones However not all isoflavones are the same. EaseFemin only uses aglycone isoflavones. Scientific studies show that aglycone isoflavones are absorbed by the human body’s cell receptors in a more efficient and faster way than regu-lar glucoside isoflavones, 4 those found in the vast majority of menopausal sup-plements in the market today. As a mat-ter of fact, one study points that agly-cone isoflavones intake were five times higher than the regular isoflavones. 4 * Synergistic Calming Herbal Blend Given that mood swings and irritability are very common during menopause, EaseFemin added a pro-prietary calming herbal blend includ-ing valerian root, chamomile and pas-sion flower. These herbs have been traditionally used for centuries not only for their calming effect, but for the observed synergistic effect on menopausal symptoms. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. References In EaseFemin, Aglycone Isoflavones are Combined From Two Sources The first is Isoƒactor™, NaturaNectar’s patent protected water-based extract from red bee propolis found only in the northeast of Brazil. The local bees natu-rally selected a native plant ( Dalbergia ecastophyllum ) to collect the resin needed for its production back in the beehives. NaturaNectar’s co-founder, Alessandro Esteves, discovered the botanical origin of this exotic propolis. 1 Recent tests per-formed by Chromadex© Laboratories on Isoƒactor unveiled that besides being a rich source of aglycone isoflavones, 2,3 Isoƒactor has powerful antioxidant activity (ORAC = 3,540 Ìmol TE/g). This very compelling for women looking to get relief from menopausal symptoms while keeping their reproduc-tive system young.* The second source is 1 Silva, B.B., Rosalen, P.L., Cury, J.A., Ikegaki, M., Souza, V.C., Esteves, A., and Alencar, S.M. Chemical Composition and Botanical Origin of Red Propolis, a New Type of Brazilian Propolis. Oxford Journals -Evidence-based Complementary and Alternative Medicine (2007) doi:10.1093/ecam/nem059. 2 Trusheva, B., Popova, M., Bankova, V., Simova, S., Marcucci, M.C., Miorin, P.L., Pasin, F.R., Tsvetkova, I. Bioactive Constituents of Brazilian Red Propolis. Oxford Journals -Evidence-based Complementary and Alternative Medicine (2006) doi:10.1093/ecam/nel006. 3 Alencar, S.M., Oldoni, T.L.C., Castro, M.L., Cabral, I.S.R., Costa-Neto, C.M.,Cury, J.A., Rosalen, P.L., Ikegakid, M. Chemical Composition and Biological Activity of a New Type of Brazilian Propolis: Red Propolis. ELSEVIER Journal of Ethno-Pharmacology (2007) JEP-4694. 4 Izumi T, Piskula MK, Osawa S, Obata A, Tobe K, Saito M, Kataoka S, Kubota Y, Kikuchi M. Soy Isoflavone Aglycones Are Absorbed Faster and in Higher Amounts than their Glucosides in Humans. The Journal of Nutrition (2000) 30(7):1695-9. 5 Boulet MJ, Odden BJ, Lehert P, Vemer HM, Visser A. Climacteric and menopause in seven southeast Asian countries. Maturitas 1994;19: 157–76. 6 Notelovitz M. Estrogen replacement therapy indications, contraindications, and agent selection. Am. J. Obstet. Gynecol. 1989; 161: 8–17. Isoflavones: Natural Alternative for Declining Hormones The daily intake of isoflavones have gained force as a viable natural alternative to HRT since 2002, when the first findings from the Women’s Health Initiative were pub-lished highlighting the health risks asso-ciated by the administration of hormone replacement therapies for menopausal women. Isoflavones are natural com-56 VITAMIN RETAILER WWW.VITAMINRETAILER.COM I NOVEMBER 2011

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